Cerebrospinal fluid penetration of amikacin in children with community-acquired bacterial meningitis
نویسندگان
چکیده
منابع مشابه
CEREBROSPINAL FLUID FINDINGS IN NEONATAL BACTERIAL MENINGITIS
Background : Meningitis is more common during the neonatal period than other periods of life and has a prevalence of one in 1000 live births. The similarity of its clinical manifestations with other infectious diseases makes it difficult to diagnose. The aim of the current study was to determine the relationship between age, sex, clinical signs and symptoms and laboratory test results of ne...
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Penetration of moxalactam into the cerebrospinal fluid was studied in 11 patients with bacterial meningitis undergoing treatment with other antibiotics. Moxalactam at a dose of 20 mg/kg was administered as three 30- to 45- min infusions at 8-h intervals, once between days 2 and 4 and a second time between days 11 and 20 of treatment with the other antibiotics. Serum and cerebrospinal fluid were...
متن کاملNo evidence of viral coinfection in cerebrospinal fluid from patients with community-acquired bacterial meningitis.
TO THE EDITOR—Bacterial meningitis is a severe disease with substantial mortality and morbidity despite the availability of effective antimicrobial agents and adjunctive therapies [1, 2]. Recently, a study involving adults with community-acquired bacterial meningitis in Malawi showed that coinfection with Epstein Barr Virus (EBV) occurred in 79 of 149 bacterial meningitis patients (53%) and tha...
متن کاملCommon Cause and Cerebrospinal Fluid Changes of Acute Bacterial Meningitis
Background and Objective: Bacterial meningitis is an important cause of mortality and long-term neural morbidity. Immediate diagnosis and treatment are necessary in appropriate time. This study was designed in Afzalipour Hospital in Kerman to evaluate meningitis causes, frequency and CSF laboratory changes. Patients and Methods: In this retrograde descriptive study from September 2003 to Se...
متن کاملPenetration of cefoxitin into cerebrospinal fluid of infants and children with bacterial meningitis.
Three consecutive doses of 75 mg of cefoxitin per kg were given intravenously every 6 h (225 mg/kg), in addition to penicillin or ampicillin, to 24 patients on days 4 and 5 and 9 and 10 of therapy for meningitis. Haemophilus influenzae b was isolated from cerebrospinal fluid (CSF) of 21 patients, Streptococcus pneumoniae from 2 patients, and Neisseria meningitidis from 1 patient. The median min...
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ژورنال
عنوان ژورنال: Antimicrobial Agents and Chemotherapy
سال: 1995
ISSN: 0066-4804,1098-6596
DOI: 10.1128/aac.39.1.253